Fluorescent Cell Chip a new in vitro approach for immunotoxicity screening.

@article{Wagner2006FluorescentCC,
  title={Fluorescent Cell Chip a new in vitro approach for immunotoxicity screening.},
  author={Waldemar Wagner and Aurelia Walczak-Drzewiecka and Aleksandra Slusarczyk and Przemysław Biecek and Leszek Rychlewski and Jarosław Dastych},
  journal={Toxicology letters},
  year={2006},
  volume={162 1},
  pages={
          55-70
        }
}
The Fluorescent Cell Chip (FCC) has been developed specifically for immunotoxicity screening of chemical compounds. This in vitro test is based on a panel of genetically modified reporter cell lines that regulate the expression of fluorescent protein in the same way as they regulate expression of cytokines. Thus, changes in fluorescence intensity represent changes in cytokine expression. Consequently, this technique conforms to efficiency expected from high throughput screening assay. In a pre… CONTINUE READING

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