Fluorescent BODIPY-labelled GM1 gangliosides designed for exploring lipid membrane properties and specific membrane-target interactions.
@article{Mikhalyov2009FluorescentBG, title={Fluorescent BODIPY-labelled GM1 gangliosides designed for exploring lipid membrane properties and specific membrane-target interactions.}, author={I. Mikhalyov and N. Gretskaya and L. Johansson}, journal={Chemistry and physics of lipids}, year={2009}, volume={159 1}, pages={ 38-44 } }
New fluorophore-labelled G(M1) gangliosides have been synthesised and spectroscopically characterised. Spectroscopically different BODIPY groups were covalently linked, specifically to either the polar or the hydrophobic part of the ganglioside molecule. The absorption and fluorescence spectroscopic properties are reported for 564/571-BODIPY- and 581/591-BODIPY-labelled G(M1). Each of the different BODIPY groups is highly fluorescent and depolarisation experiments provide molecular information… Expand
Topics from this paper
18 Citations
Lipid raft detecting in membranes of live erythrocytes.
- Chemistry, Medicine
- Biochimica et biophysica acta
- 2011
- 31
A comparative study on ganglioside micelles using electronic energy transfer, fluorescence correlation spectroscopy and light scattering techniques.
- Chemistry, Medicine
- Physical chemistry chemical physics : PCCP
- 2009
- 11
On multivalent receptor activity of GM1 in cholesterol containing membranes.
- Chemistry, Medicine
- Biochimica et biophysica acta
- 2015
- 33
New GM1 Ganglioside Derivatives for Selective Single and Double Labelling of the Natural Glycosphingolipid Skeleton
- Chemistry
- 2009
- 36
- PDF
Labeled gangliosides: their synthesis and use in biological studies
- Chemistry, Medicine
- FEBS letters
- 2018
- 3
Some patterns in dimer II formation in BODIPY-FL-labeled lipids
- Chemistry
- Russian Journal of Bioorganic Chemistry
- 2009
- 2
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes.
- Chemistry, Medicine
- Biochimica et biophysica acta
- 2012
- 261
- PDF
Photoconversion of Bodipy‐Labeled Lipid Analogues
- Chemistry, Medicine
- Chembiochem : a European journal of chemical biology
- 2013
- 12
- PDF
Continuously variable lipid packing as the principle of functional membrane heterogeneity
- Chemistry
- 2013
- Highly Influenced
- PDF
References
SHOWING 1-10 OF 25 REFERENCES
Self-aggregation – an intrinsic property of GM1 in lipid bilayers
- Chemistry, Medicine
- Molecular membrane biology
- 2007
- 39
A new chemical procedure for the preparation of gangliosides carrying fluorescent or paramagnetic probes on the lipid moiety.
- Chemistry, Medicine
- Chemistry and physics of lipids
- 1986
- 34
Characterization of cholesterol-sphingomyelin domains and their dynamics in bilayer membranes.
- Chemistry, Medicine
- Biophysical journal
- 2001
- 368
- PDF
Aggregation of an α-Helical Transmembrane Peptide in Lipid Phases, Studied by Time-Resolved Fluorescence Spectroscopy
- Chemistry
- 1999
- 18
Giant vesicles, Laurdan, and two-photon fluorescence microscopy: evidence of lipid lateral separation in bilayers.
- Chemistry, Medicine
- Methods in enzymology
- 2003
- 94
Aggregative properties of gangliosides in solution.
- Chemistry, Medicine
- Chemistry and physics of lipids
- 1994
- 93
Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions.
- Chemistry, Medicine
- Methods
- 2008
- 90
Electronic ground and excited state properties of dipyrrometheneboron difluoride (BODIPY): Dimers with application to biosciences
- Chemistry
- 2002
- 77
Dimers of dipyrrometheneboron difluoride (BODIPY) with light spectroscopic applications in chemistry and biology.
- Chemistry, Medicine
- Journal of the American Chemical Society
- 2002
- 226
Preparation of GM1 ganglioside molecular species having homogeneous fatty acid and long chain base moieties.
- Chemistry, Medicine
- Journal of lipid research
- 1985
- 106