Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.

@article{Sharwani2006FluorescenceSC,
  title={Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.},
  author={Abubkr Sharwani and Waseem K. Jerjes and Vehid Max Salih and Alexander J. Macrobert and Mohammed A El-Maaytah and Haidy S M Khalil and Colin Hopper},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2006},
  volume={83 1},
  pages={27-33}
}
BACKGROUND Early detection of premalignant/malignant lesions in the oral cavity can certainly improve the patient's prognosis. This study presents fluorescence imaging with the topical application of 5-aminolevulinic as a way to improve detection of various oral tissue pathologies. This procedure depends mainly on comparing the intensity of red and green fluorescence emitted from tissues during examination. MATERIALS AND METHODS Seventy-one patients who presented with clinically suspicious… CONTINUE READING

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