Fluorescence properties of several chemotherapy drugs: doxorubicin, paclitaxel and bleomycin.

@article{Motlagh2016FluorescencePO,
  title={Fluorescence properties of several chemotherapy drugs: doxorubicin, paclitaxel and bleomycin.},
  author={Najme Sadat Hosseini Motlagh and Parviz Parvin and Fatemah Ghasemi and Fatemeh Atyabi},
  journal={Biomedical optics express},
  year={2016},
  volume={7 6},
  pages={2400-6}
}
Several chemo-drugs act as the biocompatible fluorophores. Here, the laser induced fluorescence (LIF) properties of doxorubicin, paclitaxel and bleomycin are investigated. The absorption lines mostly lie over UV range according to the UV-VIS spectra. Therefore, a single XeCl laser provokes the desired transitions of the chemo-drugs of interest at 308 nm. It is shown that LIF spectra are strongly dependent on the fluorophore concentration giving rise to the sensible red shift. This happens when… CONTINUE READING