Fluorescence nanoscopy in cell biology

  title={Fluorescence nanoscopy in cell biology},
  author={Steffen J Sahl and Stefan W Hell and Stefan Jakobs},
  journal={Nature Reviews Molecular Cell Biology},
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the internal nanoscale structure and dynamics of cells and tissues with molecular detection specificity. While the basic physical principles of 'super-resolution' imaging were discovered in the 1990s, with initial experimental demonstrations following in 2000, the broad application of super-resolution imaging to address cell-biological questions has only more recently emerged. Nanoscopy approaches have begun to… CONTINUE READING
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