Fluorescence investigations of calmodulin hydrophobic sites.

  title={Fluorescence investigations of calmodulin hydrophobic sites.},
  author={A Follenius and Dominique G{\'e}rard},
  journal={Biochemical and biophysical research communications},
  volume={119 3},
Calmodulin activation of target enzymes depends on the interaction between calmodulin hydrophobic regions and some enzyme areas. The Ca2+ induced exposure of calmodulin hydrophobic sites was studied by means of 2-p-toluidinylnaphthalene-6-sulfonate, a fluorescent probe. Scatchard and Job plots showed that the calmodulin-Ca42+ complex bound two molecules of… CONTINUE READING