Fluorescence in situ hybridization on peripheral-blood specimens is a reliable method to evaluate cytogenetic response in chronic myeloid leukemia.

@article{Gouill2000FluorescenceIS,
  title={Fluorescence in situ hybridization on peripheral-blood specimens is a reliable method to evaluate cytogenetic response in chronic myeloid leukemia.},
  author={Steven Le Gouill and Pascaline Talmant and Noel Jean Milpied and A Daviet and M Ancelot and Philippe Moreau and Jean Luc Harousseau and R{\'e}gis Bataille and Herv{\'e} Avet-Loiseau},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2000},
  volume={18 7},
  pages={1533-8}
}
PURPOSE To evaluate the usefulness of fluorescence in situ hybridization (FISH) on peripheral-blood specimens to evaluate the cytogenetic response to treatment in patients with chronic myeloid leukemia (CML). PATIENTS AND METHODS In a first attempt, we analyzed 62 bone marrow specimens using interphase FISH and compared the results with those of… CONTINUE READING