Fluorescence in situ hybridization in the diagnosis of soft tissue neoplasms: a review.

@article{Tanas2009FluorescenceIS,
  title={Fluorescence in situ hybridization in the diagnosis of soft tissue neoplasms: a review.},
  author={Munir R. Tanas and John R. Goldblum},
  journal={Advances in anatomic pathology},
  year={2009},
  volume={16 6},
  pages={383-91}
}
This paper presents an overview of the role of fluorescence in situ hybridization (FISH) in the diagnosis of soft tissue neoplasms. Many soft tissue neoplasms harbor characteristic translocations or amplification of gene regions, which can be assessed by FISH, and can be used to assist in their diagnosis. We discuss the major morphologic categories in which FISH has come to be used including high-grade round cell sarcomas, spindle cell sarcomas, low-grade myxoid neoplasms, adipocytic neoplasms… CONTINUE READING
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