Fluorescence in situ hybridization for prenatal screening of chromosomal aneuploidies.

@article{Weise2008FluorescenceIS,
  title={Fluorescence in situ hybridization for prenatal screening of chromosomal aneuploidies.},
  author={Anja Weise and Thomas Liehr},
  journal={Expert review of molecular diagnostics},
  year={2008},
  volume={8 4},
  pages={355-7}
}
Results of a prenatal aneuploidy screening in uncultured amniocytes using FISH are available within a few hours. Thus, this so-called prenatal quick test is nowadays routinely and successfully applied to reduce psychological distress for pregnant women. The application of molecular cytogenetics for the prenatal screening of chromosomal aneuploidies overall is very reliable and has, compared with other (e.g., PCR-based) approaches, the advantage that analyses are performed on the single-cell… CONTINUE READING