Fluorescence in situ hybridization and cytogenetics of hemopoietic malignancies: new developments.

@article{Cherif1993FluorescenceIS,
  title={Fluorescence in situ hybridization and cytogenetics of hemopoietic malignancies: new developments.},
  author={Dorra Cherif and R. A. Berger},
  journal={Nouvelle revue francaise d'hematologie},
  year={1993},
  volume={35 1},
  pages={
          45-7
        }
}
Fluorescence in situ hybridization (FISH) is currently developed to analyse chromosomal abnormalities of hemopoietic malignancies in several ways: description of chromosomal rearrangements using specific probes or chromosome painting; delineation of chromosomal breakpoints with probes previously localized to chromosomal bands; hybridization to interphase nuclei to detect numerical changes and, now, some structural abnormalities. Examples of usefulness of FISH to study hemopoietic malignancies… CONTINUE READING