Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations

@article{Coniat1999FluorescenceIS,
  title={Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations},
  author={Maryvonne Busson-Le Coniat and F Salomon-Nguyen and Nicole Dastugue and Odile Maarek and Marina Lafage-Pochitaloff and M J Mozziconacci and Laurence Baranger and Françoise Brizard and Isabelle Radford and Marc Jeanpierre and O Bernard and Roland Berger},
  journal={Leukemia},
  year={1999},
  volume={13},
  pages={1975-1981}
}
Using fluorescence in situ hybridization analysis, breakpoints involving the long arm of chromosome 1 (1q) were localized in 36 patients with various hematopoietic disorders and rearrangements of the proximal part of 1q, as ascertained with banding techniques. The breakpoint was localized within the satellite II (sat II) domain in 14 patients with various abnormalities, between the sat II domain and the BCL9 locus in eight, between the BCL9 and ARNT loci in two, between sat II and ARNT in two… CONTINUE READING

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Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21

R Berger
Blood • 1998

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