Fluorescence in situ hybridization: molecular probes for diagnosis of pediatric neoplastic diseases.

Fluorescence in situ hybridization (FISH) has become an important tool for diagnosing neoplasia in children. With probes designed to identify specific chromosomes and chromosomal regions, FISH is commonly used to detect the specific chromosomal abnormalities associated with hematologic diseases and solid tumors. Variations of FISH currently being… CONTINUE READING