Fluorescence assays to study structure, dynamics, and function of RNA and RNA-ligand complexes.


With the use of computer-controlled titrators, a rapid amount of data can be taken and accurate values for stability, denaturant m ° values, and Hill coefficients can be obtained over a wide variety of conditions. Hence, CD provides a nice complement to site-resolved methods such as complementary oligonucleotide hybridization, 24 hydroxyl radical… (More)


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