Fluorescence Visualization Detection of Field Alterations in Tumor Margins of Oral Cancer Patients

@article{Poh2006FluorescenceVD,
  title={Fluorescence Visualization Detection of Field Alterations in Tumor Margins of Oral Cancer Patients},
  author={C. Poh and Lewei Zhang and Don W Anderson and J. Durham and P. M. Williams and R. Priddy and K. Berean and S. Ng and O. L. Tseng and C. MacAulay and M. Rosin},
  journal={Clinical Cancer Research},
  year={2006},
  volume={12},
  pages={6716 - 6722}
}
Purpose: Genetically altered cells could become widespread across the epithelium of patients with oral cancer, often in clinically and histologically normal tissue, and contribute to recurrent disease. Molecular approaches have begun to yield information on cancer/risk fields; tissue optics could further extend our understanding of alteration to phenotype as a result of molecular change. Experimental Design: We used a simple hand-held device in the operating room to directly visualize… Expand
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