Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays

@inproceedings{Panic2015FluorescenceluminescencebasedMF,
  title={Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays},
  author={Gordana Panic and Dayana Flores and Katrin Ingram-Sieber and Jennifer Keiser},
  booktitle={Parasites & Vectors},
  year={2015}
}
Schistosomiasis is responsible for a tremendous public health burden, yet only a single drug, praziquantel, is available. New antischistosomal treatments should therefore be developed. The accuracy, speed and objectivity of in vitro drug screening depend on the assay read-out. Microscopy is still the current gold standard and is in need of updating to an automated format. The aim of the present study was to investigate a panel of fluorescence/luminescence dyes for their applicability as… CONTINUE READING
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