Fluorescein-guided confocal laser endomicroscopy for the detection of ipilimumab-induced colitis.


Ipilimumab is an antitumor human antibody that has been very recently approved for the treatment of unresectable or metastatic melanoma [1]. By blocking the cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), ipilimumab induces Tcell activation and proliferation, resulting in an enhanced antitumor immune response [2]. The most frequent side effect of this… (More)
DOI: 10.1055/s-0031-1291603