Fluid shear stress in trabecular bone marrow due to low-magnitude high-frequency vibration.

@article{Coughlin2012FluidSS,
  title={Fluid shear stress in trabecular bone marrow due to low-magnitude high-frequency vibration.},
  author={Thomas R. Coughlin and Glen L Niebur},
  journal={Journal of biomechanics},
  year={2012},
  volume={45 13},
  pages={
          2222-9
        }
}
Low-magnitude high-frequency (LMHF) loading has recently received attention for its anabolic effect on bone. The mechanism of transmission of the anabolic signal is not fully understood, but evidence indicates that it is not dependent on bone matrix strain. One possible source of signaling is mechanostimulation of the cells in the bone marrow. We hypothesized that the magnitude of the fluid shear stress in the marrow during LMHF loading is in the mechanostimulatory range. As such, the goal of… CONTINUE READING
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