Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates.

@article{Cartwright2004FluiddynamicalBO,
  title={Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates.},
  author={Julyan H. E. Cartwright and Oreste Piro and Idan Tuval},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 19},
  pages={7234-9}
}
Experimental work in developmental biology has recently shown in mice that fluid flow driven by rotating cilia in the node, a structure present in the early stages of growth of vertebrate embryos, is responsible for determining the normal development of the left-right axis, with the heart on the left of the body, the liver on the right, and so on. The role of physics, in particular, of fluid dynamics, in the process is one of the important questions that remain to be answered. We show with an… CONTINUE READING