Fluid compartments in hemorrhaged rats after hyperosmotic crystalloid and hyperoncotic colloid resuscitation.

@article{Moon1996FluidCI,
  title={Fluid compartments in hemorrhaged rats after hyperosmotic crystalloid and hyperoncotic colloid resuscitation.},
  author={P F Moon and M A Hollyfield-Gilbert and Tanya L Myers and Taisuke Uchida and George C. Kramer},
  journal={The American journal of physiology},
  year={1996},
  volume={270 1 Pt 2},
  pages={F1-8}
}
Postresuscitation organ failure may be associated with detrimental changes in body fluid compartments. We measured how shock and resuscitation acutely alters the interstitial, cellular, and plasma compartments in different organs. Nephrectomized, anesthetized rats were bled to 50 mmHg mean arterial pressure for 1 h, followed by 60 min of resuscitation to restore blood pressure using 0.9% normal saline (NS,n = 10), 7.5% hypertonic saline (HS,n = 8), 10% hyperoncotic albumin (HA, n = 8), or 7.5… CONTINUE READING