Fluid Dynamics of Ventricular Filling in the Embryonic Heart

@article{Miller2011FluidDO,
  title={Fluid Dynamics of Ventricular Filling in the Embryonic Heart},
  author={Laura A. Miller},
  journal={Cell Biochemistry and Biophysics},
  year={2011},
  volume={61},
  pages={33-45}
}
The vertebrate embryonic heart first forms as a valveless tube that pumps blood using waves of contraction. As the heart develops, the atrium and ventricle bulge out from the heart tube, and valves begin to form through the expansion of the endocardial cushions. As a result of changes in geometry, conduction velocities, and material properties of the heart wall, the fluid dynamics and resulting spatial patterns of shear stress and transmural pressure change dramatically. Recent work suggests… CONTINUE READING
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