Fludarabine therapy in Waldenström's macroglobulinemia

  title={Fludarabine therapy in Waldenstr{\"o}m's macroglobulinemia},
  author={Renate Thalhammer-Scherrer and Klaus Geissler and Ilse Schwarzinger and Andreas Chott and Heinz Gisslinger and Paul Kn{\"o}bl and Klaus Lechner and Ulrich Jaeger},
  journal={Annals of Hematology},
 Seven patients with macroglobulinemia (six previously untreated, one with minimal pretreatment) were treated with fludarabine (25 mg/m2/day for 5 days, repeated every 4 weeks). The median age was 58 years. The time from diagnosis to treatment with fludarabine was 4.5 months to 175 months (median 32.6 months). The patients received six (n=5), five (n=1), and three (n=1) courses of fludarabine. One patient showed only a slight decrease of immunoglobulin (Ig) M (from 5750 mg/dl to 4700 mg/dl) and… CONTINUE READING
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