Fludarabine improves the therapeutic ratio of radiotherapy in mouse tumors after single-dose irradiation.

Abstract

PURPOSE Fludarabine, an adenine nucleoside analogue, and an effective inhibitor of chromosome repair, was previously shown to synergistically enhance radiation-induced regrowth delay in three murine tumors. The purpose of this study was to assess whether fludarabine can increase the therapeutic ratio of radiotherapy in murine tumors, that is, to increase… (More)

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Cite this paper

@article{Grgoire1994FludarabineIT, title={Fludarabine improves the therapeutic ratio of radiotherapy in mouse tumors after single-dose irradiation.}, author={Val{\'e}rie Gr{\'e}goire and Nathaniel Hunter and W. A. Brock and Luke Milas and William Plunkett and Walier N. Hittelman}, journal={International journal of radiation oncology, biology, physics}, year={1994}, volume={30 2}, pages={363-71} }