Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71

@article{Gao2021FludarabineII,
  title={Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71},
  author={Chengfeng Gao and Chunxia Wen and Zhifeng Li and Shuhan Lin and Shu-xian Gao and Haida Ding and Peng Zou and Zheng Xing and Yufeng Yu},
  journal={Viruses},
  year={2021},
  volume={13}
}
Viral infections are one of the leading causes in human mortality and disease. Broad-spectrum antiviral drugs are a powerful weapon against new and re-emerging viruses. However, viral resistance to existing broad-spectrum antivirals remains a challenge, which demands development of new broad-spectrum therapeutics. In this report, we showed that fludarabine, a fluorinated purine analogue, effectively inhibited infection of RNA viruses, including Zika virus, Severe fever with thrombocytopenia… Expand

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