Fludarabine, as well as 2-chlorodeoxyadenosine, can induce eosinophilia during treatment of lymphoid malignancies.

@article{Lrfars1996FludarabineAW,
  title={Fludarabine, as well as 2-chlorodeoxyadenosine, can induce eosinophilia during treatment of lymphoid malignancies.},
  author={Gerd L{\"a}rfars and A M Ud{\'e}n-Blohm{\'e} and Jan Samuelsson},
  journal={British journal of haematology},
  year={1996},
  volume={94 4},
  pages={709-12}
}
We treated 25 patients suffering from low-grade lymphoid malignancies with nucleoside analogues. In 11 patients undergoing treatment with fludarabine, two patients with follicular lymphoma developed a marked absolute peripheral blood eosinophilia devoid of clinical symptoms which resolved without medical intervention. Of 15 patients treated with 2-chlorodeoxyadenosine, one patient with B-cell chronic lymphocytic leukaemia (CLL) experienced repeated episodes of eosinophilia that required steroid… CONTINUE READING