Flucytosine resistance is restricted to a single genetic clade of Candida albicans.

@article{Pujol2004FlucytosineRI,
  title={Flucytosine resistance is restricted to a single genetic clade of Candida albicans.},
  author={Catherine Pujol and MichaelA. Pfaller and David R Soll},
  journal={Antimicrobial agents and chemotherapy},
  year={2004},
  volume={48 1},
  pages={
          262-6
        }
}
Population studies have revealed that Candida albicans can be separated into five major clades, groups I, II, III, SA, and E. Groups SA and E are highly prevalent in South Africa and Europe, respectively, while group II is excluded from the southwestern portion of the United State. In each geographical locale, several clades exist side by side, suggesting little interclade recombination. These results suggest clade-specific phenotypes. In the present study we demonstrate that resistance to… CONTINUE READING
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