Flucytosine and cryptococcosis: which in vitro test is the best predictor of outcome?

@article{Viviani2003FlucytosineAC,
  title={Flucytosine and cryptococcosis: which in vitro test is the best predictor of outcome?},
  author={Maria Anna Viviani and Maria Carmela Esposto and Massimo Cogliati and Anna Maria Tortorano},
  journal={Journal of chemotherapy},
  year={2003},
  volume={15 2},
  pages={124-8}
}
The combination of flucytosine and amphotericin B is first choice treatment for active cryptococcosis. Because of innate or acquired resistance of Cryptococcus neoformans to flucytosine, in vitro testing is mandatory. Yeast nitrogen base (YNB) at pH 7.0 is the recommended medium for the broth microdilution test (NCCLS M27-A) and for the E-test. In order to… CONTINUE READING