Fluctuations in nuclear envelope's potential mediate synchronization of early neural activity.


Neural progenitor cells and developing neurons show periodic, synchronous Ca(2+) rises even before synapse formation, and the origin of the synchronous activity remains unknown. Here, fluorescence measurement revealed that the membrane potential of the nuclear envelope, which forms an intracellular Ca(2+) store, changed with a release of Ca(2+) and… (More)
DOI: 10.1016/j.bbrc.2011.02.004