Fluctuations in circulating cell numbers following chemotherapy or bone marrow transplant.

@article{Schwegler1994FluctuationsIC,
  title={Fluctuations in circulating cell numbers following chemotherapy or bone marrow transplant.},
  author={Herbert Schwegler and Michael C. Mackey},
  journal={Journal of mathematical biology},
  year={1994},
  volume={32 8},
  pages={761-70}
}
We study the effect of noise on the behaviour of a dynamic cell population model in which cell replication and maturation take place simultaneously. We assume that the maximum proliferative potential v fluctuates uniformly about a mean value of v, and show that a decrease in v and/or the input flux uin into the population can lead to an increase in the… CONTINUE READING