Fluctuation of antiviral resistance in the intestinal tracts of nude mice infected with a mouse adenovirus.


Oral administration of adenovirus strain K87 to BALB/c nude mice resulted in viral proliferation in the intestinal tract up to around week 6 at which point replication was suppressed. In other words, the host acquired resistance. However, this resistance was temporary and the viral infection persisted over a long period with repeated periods of… (More)


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