Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity.

@article{Drew2011FluctuatingAS,
  title={Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity.},
  author={Patrick J. Drew and Andy Y. Shih and David Kleinfeld},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 20},
  pages={8473-8}
}
Neural activity in the brain is followed by localized changes in blood flow and volume. We address the relative change in volume for arteriole vs. venous blood within primary vibrissa cortex of awake, head-fixed mice. Two-photon laser-scanning microscopy was used to measure spontaneous and sensory evoked changes in flow and volume at the level of single vessels. We find that arterioles exhibit slow (<1 Hz) spontaneous increases in their diameter, as well as pronounced dilation in response to… CONTINUE READING

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Applications of spectral methods in functional brain imaging. Imaging: A Laboratory Manual, ed

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