Fluconazole vs low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant Group

@article{Wolff2000FluconazoleVL,
  title={Fluconazole vs low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant Group},
  author={Sebastien Wolff and J K Fay and Denise E. Stevens and R H Herzig and B L Pohlman and Brian James Bolwell and J W Lynch and S. C. Ericson and C O Freytes and Fred Lemaistre and R Collins and Laura Carballo Pi{\~n}eiro and J R Greer and Richard S L Stein and Sylvain Goodman and Stephen Dummer},
  journal={Bone Marrow Transplantation},
  year={2000},
  volume={25},
  pages={853-859}
}
systemic fungal infections are a major problem in bone marrow transplant recipients who have prolonged neutropenia or who receive high-dose corticosteroids. prophylaxis with fluconazole or low-dose amphotericin b reduces, but does not eliminate these infections. to determine which prophylactic agent is better, we performed a prospective randomized study. patients undergoing allogeneic (related or unrelated) or autologous marrow or peripheral stem cell transplantation were randomized to receive… CONTINUE READING

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