Fluconazole affects the alkali-metal-cation homeostasis and susceptibility to cationic toxic compounds of Candida glabrata.

@article{Elicharov2014FluconazoleAT,
  title={Fluconazole affects the alkali-metal-cation homeostasis and susceptibility to cationic toxic compounds of Candida glabrata.},
  author={Hana Elicharov{\'a} and Hana Sychrov{\'a}},
  journal={Microbiology},
  year={2014},
  volume={160 Pt 8},
  pages={1705-13}
}
Candida glabrata is a salt-tolerant and fluconazole (FLC)-resistant yeast species. Here, we analyse the contribution of plasma-membrane alkali-metal-cation exporters, a cation/proton antiporter and a cation ATPase to cation homeostasis and the maintenance of membrane potential (ΔΨ). Using a series of single and double mutants lacking CNH1 and/or ENA1 genes… CONTINUE READING