Flt-1 signaling in macrophages promotes glioma growth in vivo.

@article{Kerber2008Flt1SI,
  title={Flt-1 signaling in macrophages promotes glioma growth in vivo.},
  author={Mark Kerber and Yvonne Reiss and Anke Wickersheim and Manfred Jugold and Fabian Kiessling and Matthias Heil and Vadim Tchaikovski and Johannes Waltenberger and Masabumi Shibuya and Karl Heinz Plate and M{\'a}rcia Regina Machein},
  journal={Cancer research},
  year={2008},
  volume={68 18},
  pages={
          7342-51
        }
}
Several lines of evidence indicate that Flt-1, a fms-like tyrosine kinase receptor, which binds to vascular endothelial growth factor (VEGF)-A, VEGF-B, and PlGF, is a positive regulator of angiogenesis in the context of tumor growth and metastasis. However, the molecular basis of its action is still not clear. Besides endothelial cells, Flt-1 is also expressed by other different cell types, including myeloid hematopoeitic cells (monocytes and macrophages). To examine the functions of Flt-1… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 96 CITATIONS

FILTER CITATIONS BY YEAR

2008
2018

CITATION STATISTICS

  • 7 Highly Influenced Citations

  • Averaged 10 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Similar Papers

Loading similar papers…