Flow injection spectrophotometric determination of Al in hemodialysis solutions.

Abstract

A flow analysis (FA) system with spectrophotometric detection for Al determination in hemodialysis solutions was developed. The method was based on the reaction of Al with eriochrome cyanine R (ECR). The complex formed associated with cetyltrimethylammonium bromide (CTAB)--a cationic surfactant, which showed enough sensitivity to execute the direct analyte determination. All interferences were eliminated with the matrix matching calibration. The system presented the following analytic parameters: sensitivity (m) of 8.10 x 10(-4)L microg(-1), limit of detection (LOD) of 3.24 microg L(-1) (3sigma), linear correlation coefficient of 0.9966 and linear range response from 10.8 to 650 microg L(-1). The accuracy of the proposed method was checked by comparison with electrothermal atomic absorption spectrometry (ET-AAS) method. There were no differences among the results obtained from both methods, at a confidence level of 95% (paired t-test). Recovery tests were also made, values obtained were from 90.4 to 109 of recovery for Al-spiked samples.

Cite this paper

@article{Rodrigues2005FlowIS, title={Flow injection spectrophotometric determination of Al in hemodialysis solutions.}, author={Jairo Lisboa Rodrigues and Cristiana Schmidt de Magalh{\~a}es and Pedro Orival Luccas}, journal={Journal of pharmaceutical and biomedical analysis}, year={2005}, volume={36 5}, pages={1119-23} }