Flow injection of lithium ion using chromogenic 14-crown-4 derivatives as extraction-spectrophotometric reagents.

Abstract

A system for flow injection of Li+ has been designed, with use of proton-dissociable chromogenic 14-crown-4 derivatives as the extraction-spectrophotometric reagents, and the analytical conditions have been optimised. This flow injection system showed high selectivity for Li+ reflecting the cation-complexing property of the chromogenic crown ethers. The determination of Li+ in the clinical range in blood under a high Na+ background of 130-160 mM was feasible, with a small sample size (50 microliters) and high sampling rate (more than 100 injections per hour), with this method. The proposed extraction-spectrophotometric flow injection system was, therefore, found to be promising for the efficient determination of Li+ in biological samples, such as blood sera, with a high Na+ background.

Cite this paper

@article{Kimura1990FlowIO, title={Flow injection of lithium ion using chromogenic 14-crown-4 derivatives as extraction-spectrophotometric reagents.}, author={Koichi Kimura and Saori Iketani and Hironari Sakamoto and Tadahisa Shono}, journal={The Analyst}, year={1990}, volume={115 9}, pages={1251-5} }