Flow-induced remodeling in resistance arteries from obese Zucker rats is associated with endothelial dysfunction.

Abstract

Chronic increases in blood flow increase arterial diameter and NO-dependent dilation in resistance arteries. Because endothelial dysfunction accompanies metabolic syndrome, we hypothesized that flow-mediated remodeling might be impaired in obese rat resistance arteries. Obese and lean Zucker rat mesenteric resistance arteries were exposed to chronic flow… (More)

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@article{Bouvet2007FlowinducedRI, title={Flow-induced remodeling in resistance arteries from obese Zucker rats is associated with endothelial dysfunction.}, author={C. Bouvet and Eric J. Belin de Chantem{\`e}le and A. Guihot and Emilie Vessi{\`e}res and Arnaud Bocquet and Odile Dumont and Alain Jardel and Laurent Loufrani and Pierre Moreau and Daniel Henrion}, journal={Hypertension}, year={2007}, volume={50 1}, pages={248-54} }