Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles.

  title={Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles.},
  author={Bercan Siyahhan and Verena Knobloch and Diane de Zelicourt and M. B. Asgari and Marianne Schmid Daners and Dimos Poulikakos and Vartan Kurtcuoglu},
  journal={Journal of the Royal Society, Interface},
  volume={11 94},
While there is growing experimental evidence that cerebrospinal fluid (CSF) flow induced by the beating of ependymal cilia is an important factor for neuronal guidance, the respective contribution of vascular pulsation-driven macroscale oscillatory CSF flow remains unclear. This work uses computational fluid dynamics to elucidate the interplay between macroscale and cilia-induced CSF flows and their relative impact on near-wall dynamics. Physiological macroscale CSF dynamics are simulated in… CONTINUE READING
Highly Cited
This paper has 79 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 20 extracted citations

80 Citations

Citations per Year
Semantic Scholar estimates that this publication has 80 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 44 references

Imaging of the cerebrospinal fluid circulation

  • O Balédent
  • Adult hydrocephalus
  • 2014

Assessment of intracranial dynamics in hydrocephalus : effects of viscoelasticity on the outcome of infusion tests

  • S Bottan, M SchmidDaners, D deZelicourt, N Fellner, D Poulikakos, V Kurtcuoglu
  • J . Neurosurg .
  • 2013

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs 4

  • EJ Benner
  • Nature
  • 2013

Three - dimensional numerical simulations of human pulmonary cilia in the periciliary liquid layer by the immersed boundary method

  • PG Jayathilake, Z Tan, DV Le, HP Lee, BC Khoo
  • Comput . Fluids
  • 2012

Similar Papers

Loading similar papers…