Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles.

@article{Siyahhan2014FlowIB,
  title={Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles.},
  author={Bercan Siyahhan and Verena Knobloch and Diane de Zelicourt and M. B. Asgari and Marianne Schmid Daners and Dimos Poulikakos and Vartan Kurtcuoglu},
  journal={Journal of the Royal Society, Interface},
  year={2014},
  volume={11 94},
  pages={20131189}
}
While there is growing experimental evidence that cerebrospinal fluid (CSF) flow induced by the beating of ependymal cilia is an important factor for neuronal guidance, the respective contribution of vascular pulsation-driven macroscale oscillatory CSF flow remains unclear. This work uses computational fluid dynamics to elucidate the interplay between macroscale and cilia-induced CSF flows and their relative impact on near-wall dynamics. Physiological macroscale CSF dynamics are simulated in… CONTINUE READING
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