Flow-generating capability of the isolated skeletal muscle pump.

@article{Sheriff1998FlowgeneratingCO,
  title={Flow-generating capability of the isolated skeletal muscle pump.},
  author={Don D. Sheriff and Richard van Bibber},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={1998},
  volume={274 5},
  pages={H1502-H1508}
}
We sought to test directly whether the mechanical forces produced during rhythmic muscle contraction and relaxation act on the muscle vasculature in a manner sufficient to initiate and sustain blood flow. To accomplish this goal, we evaluated the mechanical performance of the isolated skeletal muscle pump. The hindlimb skeletal muscle pump was isolated by reversibly connecting the inferior vena cava and terminal aorta with extracorporeal tubing in 15- to 20-kg anesthetized pigs ( n = 5). During… CONTINUE READING