Flow cytometry measurement of nuclear RNA content in uveal melanoma.

@article{Chen1990FlowCM,
  title={Flow cytometry measurement of nuclear RNA content in uveal melanoma.},
  author={Tun Chen and Devron H. Char and Frederic Waldman and Richard P Juster},
  journal={Ophthalmic research},
  year={1990},
  volume={22 3},
  pages={187-93}
}
We retrospectively studied the nuclear RNA content in uveal melanomas with known, long-term follow-up. Thirty patients had spindle cell melanomas, 25 had mixed cell tumors, and 9 had epithelioid cell neoplasms. Epithelioid cell types had a higher nuclear RNA content compared to mixed or spindle cell types (p less than 0.05). Using the Cox proportional hazards model, the nuclear RNA content appeared to be an independent prognostic indicator in uveal melanomas, and an increased nuclear RNA… CONTINUE READING