Flow cytometry characterization of white cell-reduced blood: apoptosis markers and morphology of postfiltration elements.

@article{Tazzari2003FlowCC,
  title={Flow cytometry characterization of white cell-reduced blood: apoptosis markers and morphology of postfiltration elements.},
  author={Pier Luigi Tazzari and Andrea Bontadini and Fiorenza Fruet and Cristina Tassi and Francesca Ricci and Silvia Manfroi and R. N. Conte},
  journal={Vox sanguinis},
  year={2003},
  volume={85 2},
  pages={109-13}
}
BACKGROUND AND OBJECTIVES Apoptosis affects white blood cells (WBCs) contained in packed red blood cell (RBC) units. This phenomenon was recently described also in residual WBCs after filtration. The aim of this study was to better characterize the residual WBCs postfiltration by using apoptosis markers and morphology. MATERIALS AND METHODS Immunofluorescence, flow cytometry and cell-sorting techniques were utilized. RESULTS Residual leucocytes of leucodepleted packed RBC units showed… CONTINUE READING