Flow cytometry as a tool in the diagnosis of Bernard-Soulier syndrome in Brazilian patients.

@article{Beltrame2009FlowCA,
  title={Flow cytometry as a tool in the diagnosis of Bernard-Soulier syndrome in Brazilian patients.},
  author={Miriam Perlingeiro Beltrame and Mariester Malvezzi and Jos{\'e} Zanis and Ricardo Pasquini},
  journal={Platelets},
  year={2009},
  volume={20 4},
  pages={229-34}
}
Bernard-Soulier Syndrome (BSS) is an inherited recessive bleeding disorder. In some instances, diagnosis might be restricted to routine blood exams, including bleeding time, prothrombin time (PT), and partial thromboplastin time (APTT). Exams such as platelet aggregation, and testing for expression of ristocetin cofactor, or von Willebrand factor may not be commonly performed. This leads to misdiagnosis in a number of patients, which are subsequently treated erroneously. Flow cytometry has been… CONTINUE READING