Flow cytometric measurement of intracellular migration inhibition factor and tumour necrosis factor alpha in the mucosa of patients with coeliac disease.

@article{OKeeffe2001FlowCM,
  title={Flow cytometric measurement of intracellular migration inhibition factor and tumour necrosis factor alpha in the mucosa of patients with coeliac disease.},
  author={Jean O'Keeffe and Sara Lynch and Alex Whelan and J. J. Jackson and Nicholas P Kennedy and Donald George Weir and Conleth Feighery},
  journal={Clinical and experimental immunology},
  year={2001},
  volume={125 3},
  pages={376-82}
}
There is increasing evidence that proinflammatory cytokines contribute to many of the small intestinal features in coeliac disease. The aim of the study was to investigate the expression of two proinflammatory cytokines, migration inhibition factor (MIF) and tumour necrosis factor alpha (TNF-alpha) in duodenal biopsy specimens from patients with coeliac disease on a gluten-free diet and normal control subjects. A flow cytometric system was used to analyse intracellular protein levels of MIF and… CONTINUE READING

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