Flow cytometric estimation of the effect of Ginkgo biloba extract on the content of hydrogen peroxide in dissociated mammalian brain neurons.

@article{Oyama1992FlowCE,
  title={Flow cytometric estimation of the effect of Ginkgo biloba extract on the content of hydrogen peroxide in dissociated mammalian brain neurons.},
  author={Y. Oyama and T. Ueha and A. Hayashi and L. Chikahisa and K. Noda},
  journal={Japanese journal of pharmacology},
  year={1992},
  volume={60 4},
  pages={
          385-8
        }
}
  • Y. Oyama, T. Ueha, +2 authors K. Noda
  • Published 1992
  • Chemistry, Medicine
  • Japanese journal of pharmacology
  • The effect of Ginkgo biloba extract (GBE) on the content of hydrogen peroxide was estimated in cerebellar neurons dissociated from rats, by means of a flow-cytometer and 2',7'-dichlorofluorescein (DCF) diacetate, a fluorescent dye for intracellular hydrogen peroxide. The GBE started to reduce the DCF fluorescence of the neuron at 0.1 microgram/ml to 0.3 microgram/ml. Further increases in the GBE concentration (up to 3 micrograms/ml) produced a dose-dependent decrease in the DCF fluorescence… CONTINUE READING

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