Flow cytometric detection of progastrin interaction with gastrointestinal cells.

Abstract

The unprocessed gastrin precursor, progastrin (PG), is often overexpressed in colon cancer and other malignancies where it appears to stimulate colonic growth. Overexpression of progastrin also stimulates proliferation of normal colonic mucosa, but the receptors mediating these effects have not been identified. Here we report the development of a non… (More)
DOI: 10.1016/j.regpep.2008.07.001

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