Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques.

@article{Morice2004FlowCA,
  title={Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques.},
  author={William G. Morice and Teresa K. Kimlinger and Jerry A. Katzmann and John A. Lust and Paul J Heimgartner and Kevin C. Halling and Curtis A. Hanson},
  journal={American journal of clinical pathology},
  year={2004},
  volume={121 3},
  pages={373-83}
}
Molecular genetic T-cell receptor (TCR) and flow cytometric analysis using antibodies to conventional T-cell antigens and TCR beta-chain variable region families (TCR-Vbeta) were performed in 65 peripheral blood specimens evaluated for potential involvement by a T-cell lymphoproliferative disorder (TCLPD). A normal or reactive conventional T-cell immunophenotype was present in 36 cases; TCR-Vbeta flow cytometric and molecular TCR analyses were negative for clonality in 32 and 27 of these cases… CONTINUE READING
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Pathology and Genetics of Tumours of Haematopoetic and Lymphoid Tissues

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