Flow cytometric analysis of nuclear DNA content in gestational trophoblastic disease.

@article{Lage1991FlowCA,
  title={Flow cytometric analysis of nuclear DNA content in gestational trophoblastic disease.},
  author={Janice M. Lage},
  journal={The Journal of reproductive medicine},
  year={1991},
  volume={36 1},
  pages={31-5}
}
Flow cytometric analysis of nuclear DNA is a quick and accurate method of determining nuclear ploidy. This technique allows a clear distinction to be made between diploid and triploid hydatidiform moles. Additional ploidy aberrations, such as tetraploidy and aneuploidy, have also been reported in flow cytometric studies of hydatidiform moles. Recent investigations have suggested that aneuploidy in complete hydatidiform moles is associated with a high risk of persistent gestational trophoblastic… CONTINUE READING

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