Flow cytometric analysis of hematopoietic development.

More than 30 yr ago, a collection of cells isolated from the bone marrow were first demonstrated to repopulate hematopoiesis in a radioablated animal. These cells self- renewed while producing all of the blood products and were named hematopoietic stem cells (HSCs). Since then, HSCs have been a tremendous boon to both basic science in understanding cell… CONTINUE READING