Flow cytometric analysis of adrenal cortical tumor DNA. Relationship between cellular DNA and histopathologic classification.

@article{Bowlby1986FlowCA,
  title={Flow cytometric analysis of adrenal cortical tumor DNA. Relationship between cellular DNA and histopathologic classification.},
  author={L S Bowlby and L E Debault and Sajith Abraham},
  journal={Cancer},
  year={1986},
  volume={58 7},
  pages={1499-505}
}
Nuclear DNA contents of 22 paraffin-embedded adrenal cortical tumors (16 adenomas and 6 carcinomas) were determined by flow cytometric analysis. While all of the sixteen adenomas had a diploid pattern, 83.3% (5/6) of the carcinomas were aneuploid. Three of the six patients with carcinomas (50%) developed metastases and died of their disease; all had… CONTINUE READING