Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells.

@article{Drudy2001FlowCA,
  title={Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells.},
  author={Denise Drudy and Dennis P. Odonoghue and A Baird and L. Fenelon and Cliona O'Farrelly},
  journal={Journal of medical microbiology},
  year={2001},
  volume={50 6},
  pages={
          526-34
        }
}
Clostridium difficile is the most common cause of diarrhoea in hospitalised patients. Bacterial adherence to gut epithelial cells is a likely prerequisite to infection and toxin production. A novel flow cytometric method was developed for detecting adherence of C. difficile to human colonic and small intestinal epithelial cells (EC) and human intestinal cell lines. Small intestinal and colonic EC were isolated from biopsy specimens with mucolytic and chelating agents. Adherence of fluorochrome… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Clostridium difficile infection in the postcolectomy patient.

  • Inflammatory bowel diseases
  • 2014
VIEW 1 EXCERPT
CITES BACKGROUND