Flow control valves for analytical microfluidic chips without mechanical parts based on thermally responsive monolithic polymers.

@article{Yu2003FlowCV,
  title={Flow control valves for analytical microfluidic chips without mechanical parts based on thermally responsive monolithic polymers.},
  author={Cong Yu and Senol Mutlu and Ponnambalam Ravi Selvaganapathy and Carlos H. Mastrangelo and Frantisek Svec and Jean M. J. Fr{\'e}chet},
  journal={Analytical chemistry},
  year={2003},
  volume={75 8},
  pages={
          1958-61
        }
}
  • Cong Yu, Senol Mutlu, +3 authors Jean M. J. Fréchet
  • Published 2003
  • Medicine, Chemistry
  • Analytical chemistry
  • Monolithic plugs of poly(N-isopropylacrylamide) cross-linked with 5% methylenebisacrylamide have been prepared by photoinitiated polymerization within the channel of a microfluidic device. The volume change associated with the polymer phase transition at its lower critical solution temperature of 32 degrees C allows both the rapid swelling and the deswelling of the monoliths enabling the polymer to close or open the channel as it functions as a nonmechanical valve. Thermoelectric elements… CONTINUE READING

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    Advances in Polymer Science; Responsive Gels: Volume Transitions II